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BDBM50349340 CHEMBL1809246

SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCOCC2)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=RMWXGWVSUPXDID-RPWUZVMVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349340   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349340
PNG
(CHEMBL1809246)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCOCC2)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C28H36N6O6S/c29-26(30)22-10-8-20(9-11-22)18-31-27(36)24-7-4-12-34(24)28(37)23(17-25(35)33-13-15-40-16-14-33)32-41(38,39)19-21-5-2-1-3-6-21/h1-3,5-6,8-11,23-24,32H,4,7,12-19H2,(H3,29,30)(H,31,36)/t23-,24+/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
 183n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair