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BDBM50349353 CHEMBL1809259

SMILES: [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7]

InChI Key: InChIKey=JCMLGDHLWHMJCR-UXHICEINSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349353   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349353
PNG
(CHEMBL1809259)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H](-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r|
Show InChI InChI=1S/C24H33N7O5S/c25-23(26)18-10-8-16(9-11-18)14-30-20(13-21(32)33)22(34)19(7-4-12-29-24(27)28)31-37(35,36)15-17-5-2-1-3-6-17/h1-3,5-6,8-11,19-20,30-31H,4,7,12-15H2,(H3,25,26)(H,32,33)(H4,27,28,29)/t19-,20+/m1/s1
KEGG

UniProtKB/SwissProt

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Article
PubMed
 422n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair