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BDBM50349360 CHEMBL1809212

SMILES: NC(=N)c1ccc(CNC(=O)[C@H](CCCCNC(=O)OCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=GMDXFLHYFNALDU-WUFINQPMSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349360   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349360
PNG
(CHEMBL1809212)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCCCNC(=O)OCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C32H40N6O7S/c33-29(34)26-16-14-23(15-17-26)19-36-30(40)27(13-7-8-18-35-32(42)45-21-24-9-3-1-4-10-24)37-31(41)28(20-39)38-46(43,44)22-25-11-5-2-6-12-25/h1-6,9-12,14-17,27-28,38-39H,7-8,13,18-22H2,(H3,33,34)(H,35,42)(H,36,40)(H,37,41)/t27-,28+/m0/s1
KEGG

UniProtKB/SwissProt

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Similars
Article
PubMed
 51n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair