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BDBM50349369 CHEMBL1809236

SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)C#N)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=UKHADIJBUYJNGB-SXOMAYOGSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349369   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349369
PNG
(CHEMBL1809236)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)C#N)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C30H32N6O4S/c31-18-22-10-8-21(9-11-22)17-26(35-41(39,40)20-24-5-2-1-3-6-24)30(38)36-16-4-7-27(36)29(37)34-19-23-12-14-25(15-13-23)28(32)33/h1-3,5-6,8-15,26-27,35H,4,7,16-17,19-20H2,(H3,32,33)(H,34,37)/t26-,27+/m1/s1
KEGG

UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 311n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair