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SMILES: [#6]-[#8]-c1cc(-[#8]-[#6])c(cc1-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@H]-1-[#6]-[#8]-c2cc(-[#8])ccc2-[#6]-1=O

InChI Key: InChIKey=NJYHQLKQBUJZIS-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50349924
PNG
(CHEMBL1811965)
Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c(cc1-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@H]-1-[#6]-[#8]-c2cc(-[#8])ccc2-[#6]-1=O |r|
Show InChI InChI=1S/C22H24O5/c1-13(2)5-6-14-9-17(20(26-4)11-19(14)25-3)18-12-27-21-10-15(23)7-8-16(21)22(18)24/h5,7-11,18,23H,6,12H2,1-4H3/t18-/m1/s1
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Similars
Article
PubMed
n/an/a 1.52E+4n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 mins

Bioorg Med Chem 19: 3378-83 (2011)


Article DOI: 10.1016/j.bmc.2011.04.037
BindingDB Entry DOI: 10.7270/Q2DF6RKT
More data for this
Ligand-Target Pair