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SMILES: CC1COC2=CC(=O)C(=O)c3cccc1c23

InChI Key: InChIKey=DBCUFRYAUMHTRE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349934   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50349934
PNG
(CHEMBL1812139)
Show SMILES CC1COC2=CC(=O)C(=O)c3cccc1c23 |t:4|
Show InChI InChI=1S/C13H10O3/c1-7-6-16-11-5-10(14)13(15)9-4-2-3-8(7)12(9)11/h2-5,7H,6H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.88E+3n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis

Eur J Med Chem 46: 3339-47 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.059
BindingDB Entry DOI: 10.7270/Q2513ZJD
More data for this
Ligand-Target Pair