BDBM50349939 CHEMBL1812176

SMILES: FC(F)(F)c1cccc(c1)N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1

InChI Key: InChIKey=KAKXZGCXRHGJOI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50349939 (CHEMBL1812176) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1 Show InChI InChI=1S/C24H22F3N5O/c25-24(26,27)17-4-3-5-18(14-17)31-11-8-30(9-12-31)10-13-32-16-29-22-19-6-1-2-7-21(19)28-15-20(22)23(32)33/h1-7,14-16H,8-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Lodz Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay				Eur J Med Chem 46: 3348-61 (2011) Article DOI: 10.1016/j.ejmech.2011.04.060 BindingDB Entry DOI: 10.7270/Q21836VH
					More data for this Ligand-Target Pair