BDBM50349999 CHEMBL1813037

SMILES: CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)OCc2ccccc2F)c1C

InChI Key: InChIKey=OBPYTQFWLKNKCZ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50349999 (CHEMBL1813037) Show SMILES CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)OCc2ccccc2F)c1C Show InChI InChI=1S/C24H27FN6O2/c1-16-21(28-17(2)32)8-5-9-22(16)29-23-26-15-27-24(30-23)31-12-10-19(11-13-31)33-14-18-6-3-4-7-20(18)25/h3-9,15,19H,10-14H2,1-2H3,(H,28,32)(H,26,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair