BDBM50350000 CHEMBL1813036

SMILES: CC(OC1CCN(CC1)c1ncnc(Nc2cccc(NC(C)=O)c2C)n1)c1ccccc1

InChI Key: InChIKey=WCPRJQTYVCDHQN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50350000 (CHEMBL1813036) Show SMILES CC(OC1CCN(CC1)c1ncnc(Nc2cccc(NC(C)=O)c2C)n1)c1ccccc1 Show InChI InChI=1S/C25H30N6O2/c1-17-22(28-19(3)32)10-7-11-23(17)29-24-26-16-27-25(30-24)31-14-12-21(13-15-31)33-18(2)20-8-5-4-6-9-20/h4-11,16,18,21H,12-15H2,1-3H3,(H,28,32)(H,26,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair