BDBM50350002 CHEMBL1813034

SMILES: CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)c2ccccc2)c1C

InChI Key: InChIKey=MWPVVPNPUHSSMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50350002 (CHEMBL1813034) Show SMILES CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)c2ccccc2)c1C Show InChI InChI=1S/C23H26N6O/c1-16-20(26-17(2)30)9-6-10-21(16)27-22-24-15-25-23(28-22)29-13-11-19(12-14-29)18-7-4-3-5-8-18/h3-10,15,19H,11-14H2,1-2H3,(H,26,30)(H,24,25,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair