BDBM50350011 CHEMBL1813025

SMILES: COC1CCN(CC1)c1ncnc(Nc2cccc(NC(C)=O)c2)n1

InChI Key: InChIKey=SVRVOJYAOQTIMN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50350011 (CHEMBL1813025) Show SMILES COC1CCN(CC1)c1ncnc(Nc2cccc(NC(C)=O)c2)n1 Show InChI InChI=1S/C17H22N6O2/c1-12(24)20-13-4-3-5-14(10-13)21-16-18-11-19-17(22-16)23-8-6-15(25-2)7-9-23/h3-5,10-11,15H,6-9H2,1-2H3,(H,20,24)(H,18,19,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assay				J Med Chem 54: 4427-45 (2011) Article DOI: 10.1021/jm200018k BindingDB Entry DOI: 10.7270/Q2N016W1
					More data for this Ligand-Target Pair