BDBM50350070 CHEMBL1813633

SMILES: COc1ccc(cc1)-c1csc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12

InChI Key: InChIKey=IWBCSBLGBURCQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50350070 (CHEMBL1813633) Show SMILES COc1ccc(cc1)-c1csc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI InChI=1S/C31H20F2N4O4S/c1-40-22-11-4-18(5-12-22)24-16-42-30-27(24)29(34-17-35-30)41-26-13-8-20(15-25(26)33)36-28(38)23-3-2-14-37(31(23)39)21-9-6-19(32)7-10-21/h2-17H,1H3,(H,36,38)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met after 60 mins by ELISA				Bioorg Med Chem 19: 3906-18 (2011) Article DOI: 10.1016/j.bmc.2011.05.038 BindingDB Entry DOI: 10.7270/Q2CF9QGW
					More data for this Ligand-Target Pair