BDBM50350079 CHEMBL1813645

SMILES: Cc1coc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12

InChI Key: InChIKey=LBOSDQIRNSVLLV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50350079 (CHEMBL1813645) Show SMILES Cc1coc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI InChI=1S/C25H16F2N4O4/c1-14-12-34-23-21(14)24(29-13-28-23)35-20-9-6-16(11-19(20)27)30-22(32)18-3-2-10-31(25(18)33)17-7-4-15(26)5-8-17/h2-13H,1H3,(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met after 60 mins by ELISA				Bioorg Med Chem 19: 3906-18 (2011) Article DOI: 10.1016/j.bmc.2011.05.038 BindingDB Entry DOI: 10.7270/Q2CF9QGW
					More data for this Ligand-Target Pair