BDBM50350149 CHEMBL1814312

SMILES: COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O

InChI Key: InChIKey=KNYQXFHNRYTONS-UHFFFAOYSA-N

Data: 1 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50350149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50350149 (CHEMBL1814312) Show SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O Show InChI InChI=1S/C21H23NO3/c1-5-7-15-11-18(21(24)19(12-15)22-14(3)23)16-9-10-20(25-4)17(13-16)8-6-2/h5-6,9-13,24H,1-2,7-8H2,3-4H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 2 hrs				Eur J Med Chem 116: 252-266 (2016) Article DOI: 10.1016/j.ejmech.2016.03.072 BindingDB Entry DOI: 10.7270/Q2DJ5HHP
					More data for this Ligand-Target Pair
GABA-A receptor; GABA-A site (alpha1/beta2 interface) (Homo sapiens (Human))	BDBM50350149 (CHEMBL1814312) Show SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O Show InChI InChI=1S/C21H23NO3/c1-5-7-15-11-18(21(24)19(12-15)22-14(3)23)16-9-10-20(25-4)17(13-16)8-6-2/h5-6,9-13,24H,1-2,7-8H2,3-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...				J Med Chem 54: 5349-61 (2011) Article DOI: 10.1021/jm200186n BindingDB Entry DOI: 10.7270/Q2QR4XGP
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50350149 (CHEMBL1814312) Show SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O Show InChI InChI=1S/C21H23NO3/c1-5-7-15-11-18(21(24)19(12-15)22-14(3)23)16-9-10-20(25-4)17(13-16)8-6-2/h5-6,9-13,24H,1-2,7-8H2,3-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Allosteric modulation of GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induc...				Bioorg Med Chem 23: 6757-62 (2015) BindingDB Entry DOI: 10.7270/Q2WQ05KM
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50350149 (CHEMBL1814312) Show SMILES COc1ccc(cc1CC=C)-c1cc(CC=C)cc(NC(C)=O)c1O Show InChI InChI=1S/C21H23NO3/c1-5-7-15-11-18(21(24)19(12-15)22-14(3)23)16-9-10-20(25-4)17(13-16)8-6-2/h5-6,9-13,24H,1-2,7-8H2,3-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.81E+4	n/a	n/a	n/a	n/a
University of Graz Curated by ChEMBL					Assay Description Partial agonist activity at GABAAalpha1beta2gamma2s receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as induction of chloride c...				Bioorg Med Chem 23: 6757-62 (2015) BindingDB Entry DOI: 10.7270/Q2WQ05KM
					More data for this Ligand-Target Pair