BDBM50350309 CHEMBL1812662
SMILES: CC([NH3+])(CCCCB(O)O)C([O-])=O
InChI Key: InChIKey=VJCNFQNUKLFMMR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase (Plasmodium falciparum) | BDBM50350309 (CHEMBL1812662) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assay | J Med Chem 54: 5432-43 (2011) Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50350309 (CHEMBL1812662) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) Article DOI: 10.1016/j.bmcl.2013.02.024 BindingDB Entry DOI: 10.7270/Q22J6D8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-2, mitochondrial (Homo sapiens (Human)) | BDBM50350309 (CHEMBL1812662) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery Curated by ChEMBL | Assay Description Inhibition of human Arg2 by colorimetric assay | Bioorg Med Chem Lett 23: 2027-30 (2013) Article DOI: 10.1016/j.bmcl.2013.02.024 BindingDB Entry DOI: 10.7270/Q22J6D8K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50350309 (CHEMBL1812662) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a |
Drexel University Curated by ChEMBL | Assay Description Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assay | J Med Chem 54: 5432-43 (2011) Article DOI: 10.1021/jm200443b BindingDB Entry DOI: 10.7270/Q2TH8N21 | |||||||||||
More data for this Ligand-Target Pair |