BDBM50350361 CHEMBL1813289
SMILES: Cc1c(CC(O)=O)c2cc(F)ccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc23)cc1C
InChI Key: InChIKey=NVDILWSBQQABQM-GOSISDBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid DP receptor (Mus musculus) | BDBM50350361 (CHEMBL1813289) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Bioorg Med Chem 19: 4574-88 (2011) Article DOI: 10.1016/j.bmc.2011.06.014 BindingDB Entry DOI: 10.7270/Q2FB5398 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50350361 (CHEMBL1813289) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation counting | Bioorg Med Chem 19: 4574-88 (2011) Article DOI: 10.1016/j.bmc.2011.06.014 BindingDB Entry DOI: 10.7270/Q2FB5398 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid DP receptor (Mus musculus) | BDBM50350361 (CHEMBL1813289) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu... | Bioorg Med Chem 19: 4574-88 (2011) Article DOI: 10.1016/j.bmc.2011.06.014 BindingDB Entry DOI: 10.7270/Q2FB5398 | |||||||||||
More data for this Ligand-Target Pair |