BDBM50350473 Aliporina::CEFALORIDINE
SMILES: [O-]C(=O)C1=C(C[n+]2ccccc2)CS[C@@H]2[C@@H](NC(=O)Cc3cccs3)C(=O)N12
InChI Key: InChIKey=CZTQZXZIADLWOZ-MAUKXSAKSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Solute carrier family 22 member 6 (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells | Eur J Pharmacol 438: 137-42 (2002) BindingDB Entry DOI: 10.7270/Q2N87C2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 8 (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells | Eur J Pharmacol 438: 137-42 (2002) BindingDB Entry DOI: 10.7270/Q2N87C2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 11 (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 3.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells | Eur J Pharmacol 438: 137-42 (2002) BindingDB Entry DOI: 10.7270/Q2N87C2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter, kidney isoform (Rattus norvegicus) | BDBM50350473 (Aliporina | CEFALORIDINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells | Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 6 (Rattus norvegicus) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | 2.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes | J Pharmacol Exp Ther 290: 672-7 (1999) BindingDB Entry DOI: 10.7270/Q2H41SJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 2 (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano Curated by ChEMBL | Assay Description Binding affinity to human PepT2 in SKTP cells | Bioorg Med Chem 19: 4544-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells | Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 7 (Homo sapiens (Human)) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 4.48E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells | Eur J Pharmacol 465: 1-7 (2003) BindingDB Entry DOI: 10.7270/Q2CC11SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 7 (Rattus norvegicus) | BDBM50350473 (Aliporina | CEFALORIDINE) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | >5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells | Eur J Pharmacol 465: 1-7 (2003) BindingDB Entry DOI: 10.7270/Q2CC11SX | |||||||||||
More data for this Ligand-Target Pair |