BDBM50350680 CHEMBL1813770

SMILES: C1COc2cc(ccc2O1)-c1nnc(\C=C\c2ccccc2)o1

InChI Key: InChIKey=JMZPOQKXFUVCCN-RMKNXTFCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50350680 (CHEMBL1813770) Show SMILES C1COc2cc(ccc2O1)-c1nnc(\C=C\c2ccccc2)o1 Show InChI InChI=1S/C18H14N2O3/c1-2-4-13(5-3-1)6-9-17-19-20-18(23-17)14-7-8-15-16(12-14)22-11-10-21-15/h1-9,12H,10-11H2/b9-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation counting				Bioorg Med Chem 19: 4895-902 (2011) Article DOI: 10.1016/j.bmc.2011.06.061 BindingDB Entry DOI: 10.7270/Q23T9HK2
					More data for this Ligand-Target Pair