BDBM50350804 CHEMBL1819128
SMILES: COc1cc2ncnc(N3CCCC(C3)c3ccccc3)c2cc1OCCc1ccccn1
InChI Key: InChIKey=DWBBOQWADWMQGE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat)) | BDBM50350804 (CHEMBL1819128) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 247 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant rat PDE10A expressed in Sf9 cells using [3H]cAMP after 30 mins by scintillation proximity assay | J Med Chem 54: 4536-47 (2011) Article DOI: 10.1021/jm2001508 BindingDB Entry DOI: 10.7270/Q2PN961Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |