BDBM50350813 CHEMBL1819141
SMILES: CCCN(CCc1c[nH]c2ccccc12)Cc1ccc(\C=C\C(=O)NO)cc1
InChI Key: InChIKey=BQCWQIOZJSBQCJ-VAWYXSNFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50350813 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50350813
(CHEMBL1819141)Show SMILES CCCN(CCc1c[nH]c2ccccc12)Cc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C23H27N3O2/c1-2-14-26(15-13-20-16-24-22-6-4-3-5-21(20)22)17-19-9-7-18(8-10-19)11-12-23(27)25-28/h3-12,16,24,28H,2,13-15,17H2,1H3,(H,25,27)/b12-11+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by radioligand binding assay |
J Med Chem 54: 4752-72 (2011)
Article DOI: 10.1021/jm200388e
BindingDB Entry DOI: 10.7270/Q23N24DW |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50350813
(CHEMBL1819141)Show SMILES CCCN(CCc1c[nH]c2ccccc12)Cc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C23H27N3O2/c1-2-14-26(15-13-20-16-24-22-6-4-3-5-21(20)22)17-19-9-7-18(8-10-19)11-12-23(27)25-28/h3-12,16,24,28H,2,13-15,17H2,1H3,(H,25,27)/b12-11+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
J Med Chem 54: 4752-72 (2011)
Article DOI: 10.1021/jm200388e
BindingDB Entry DOI: 10.7270/Q23N24DW |
More data for this
Ligand-Target Pair | |
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