BDBM50351052 CHEMBL1819466
SMILES: COc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(cc3c2=O)-c2ccc(OCc3ccccc3)cc2)CC1
InChI Key: InChIKey=HCXQFLAZMPDFTD-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50351052 (CHEMBL1819466) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 784 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Catania Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry | Bioorg Med Chem 19: 5260-76 (2011) Article DOI: 10.1016/j.bmc.2011.06.043 BindingDB Entry DOI: 10.7270/Q2D50NBD | |||||||||||
More data for this Ligand-Target Pair |