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BDBM50351061 CHEMBL1819475

SMILES: COc1ccc(cc1)-c1cc2c([nH]1)n(Cc1ccccc1OC)c(=O)n(CCN1CCN(CC1)c1ccccc1Cl)c2=O

InChI Key: InChIKey=SSDZREHTUPIFSA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351061   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50351061
PNG
(CHEMBL1819475)
Show SMILES COc1ccc(cc1)-c1cc2c([nH]1)n(Cc1ccccc1OC)c(=O)n(CCN1CCN(CC1)c1ccccc1Cl)c2=O
Show InChI InChI=1S/C33H34ClN5O4/c1-42-25-13-11-23(12-14-25)28-21-26-31(35-28)39(22-24-7-3-6-10-30(24)43-2)33(41)38(32(26)40)20-17-36-15-18-37(19-16-36)29-9-5-4-8-27(29)34/h3-14,21,35H,15-20,22H2,1-2H3
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PC sid
UniChem

Similars
Article
PubMed
 4.67E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry

Bioorg Med Chem 19: 5260-76 (2011)


Article DOI: 10.1016/j.bmc.2011.06.043
BindingDB Entry DOI: 10.7270/Q2D50NBD
More data for this
Ligand-Target Pair