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BDBM50351065 CHEMBL1819455

SMILES: CC(C)(C)c1cc2[nH]c(=O)n(CCN3CCN(CC3)c3ccccc3Cl)c(=O)c2[nH]1

InChI Key: InChIKey=BEFKXOLYWQVSKG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351065   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50351065
PNG
(CHEMBL1819455)
Show SMILES CC(C)(C)c1cc2[nH]c(=O)n(CCN3CCN(CC3)c3ccccc3Cl)c(=O)c2[nH]1
Show InChI InChI=1S/C22H28ClN5O2/c1-22(2,3)18-14-16-19(25-18)20(29)28(21(30)24-16)13-10-26-8-11-27(12-9-26)17-7-5-4-6-15(17)23/h4-7,14,25H,8-13H2,1-3H3,(H,24,30)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 65.2n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5HT1A in CRL:CD(SD)BR-COBS rat brain hippocampus after 30 mins by liquid scintillation spectrometry

Bioorg Med Chem 19: 5260-76 (2011)


Article DOI: 10.1016/j.bmc.2011.06.043
BindingDB Entry DOI: 10.7270/Q2D50NBD
More data for this
Ligand-Target Pair