BDBM50351143 CHEMBL1817906

SMILES: COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O

InChI Key: InChIKey=HLHQOBKYMAPHIA-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50351143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50351143 (CHEMBL1817906) Show SMILES COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O |c:4,t:2| Show InChI InChI=1S/C16H15N5O5S2/c1-26-16-4-2-3-15-20(16)11-5-7-19-10-14(11)28(24,25)21(15)12-6-8-18-9-13(12)27(17,22)23/h2-10,15H,1H3,(H2,17,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 46: 4403-10 (2011) Article DOI: 10.1016/j.ejmech.2011.07.011 BindingDB Entry DOI: 10.7270/Q2RF5VDJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50351143 (CHEMBL1817906) Show SMILES COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O |c:4,t:2| Show InChI InChI=1S/C16H15N5O5S2/c1-26-16-4-2-3-15-20(16)11-5-7-19-10-14(11)28(24,25)21(15)12-6-8-18-9-13(12)27(17,22)23/h2-10,15H,1H3,(H2,17,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 46: 4403-10 (2011) Article DOI: 10.1016/j.ejmech.2011.07.011 BindingDB Entry DOI: 10.7270/Q2RF5VDJ
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIV (Homo sapiens (Human))	BDBM50351143 (CHEMBL1817906) Show SMILES COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O |c:4,t:2| Show InChI InChI=1S/C16H15N5O5S2/c1-26-16-4-2-3-15-20(16)11-5-7-19-10-14(11)28(24,25)21(15)12-6-8-18-9-13(12)27(17,22)23/h2-10,15H,1H3,(H2,17,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	76.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 46: 4403-10 (2011) Article DOI: 10.1016/j.ejmech.2011.07.011 BindingDB Entry DOI: 10.7270/Q2RF5VDJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50351143 (CHEMBL1817906) Show SMILES COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O |c:4,t:2| Show InChI InChI=1S/C16H15N5O5S2/c1-26-16-4-2-3-15-20(16)11-5-7-19-10-14(11)28(24,25)21(15)12-6-8-18-9-13(12)27(17,22)23/h2-10,15H,1H3,(H2,17,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 46: 4403-10 (2011) Article DOI: 10.1016/j.ejmech.2011.07.011 BindingDB Entry DOI: 10.7270/Q2RF5VDJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50351143 (CHEMBL1817906) Show SMILES COC1=CC=CC2N1c1ccncc1S(=O)(=O)N2c1ccncc1S(N)(=O)=O |c:4,t:2| Show InChI InChI=1S/C16H15N5O5S2/c1-26-16-4-2-3-15-20(16)11-5-7-19-10-14(11)28(24,25)21(15)12-6-8-18-9-13(12)27(17,22)23/h2-10,15H,1H3,(H2,17,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 46: 4403-10 (2011) Article DOI: 10.1016/j.ejmech.2011.07.011 BindingDB Entry DOI: 10.7270/Q2RF5VDJ
					More data for this Ligand-Target Pair