BDBM50351256 CHEMBL1818526
SMILES: N[C@H](CO)CSC(c1ccccc1)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=ZBGBEDOUDIAIHO-OAQYLSRUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein 1 (Homo sapiens (Human)) | BDBM50351256 (CHEMBL1818526) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 294 | n/a | n/a | n/a | n/a |
New Mexico State University Curated by ChEMBL | Assay Description Inhibition of KSP in human HeLa cells assessed as bipolar spindle formation | Bioorg Med Chem 19: 5446-53 (2011) Article DOI: 10.1016/j.bmc.2011.07.054 BindingDB Entry DOI: 10.7270/Q2KP82HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein 1 (Homo sapiens (Human)) | BDBM50351256 (CHEMBL1818526) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
New Mexico State University Curated by ChEMBL | Assay Description Inhibition of human recombinant microtubule-activated KSP motor domain ATPase activity after 10 mins by end-point assay | Bioorg Med Chem 19: 5446-53 (2011) Article DOI: 10.1016/j.bmc.2011.07.054 BindingDB Entry DOI: 10.7270/Q2KP82HC | |||||||||||
More data for this Ligand-Target Pair |