BDBM50351477 CHEMBL1819605

SMILES: CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12

InChI Key: InChIKey=XBQDNUNBWGAMTQ-NRFANRHFSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50351477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP2 Receptor (Mus musculus (Mouse))	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse prostaglandin EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Mus musculus)	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair
Prostanoid EP4 Receptor (Mus musculus (Mouse))	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse prostaglandin EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse prostaglandin EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair
Prostanoid EP1 Receptor (Mus musculus (Mouse))	BDBM50351477 (CHEMBL1819605) Show SMILES CN1C[C@@H](COc2ccc(NC(=O)c3cccc(CC(O)=O)c3)cc2)Oc2ccccc12 |r| Show InChI InChI=1S/C25H24N2O5/c1-27-15-21(32-23-8-3-2-7-22(23)27)16-31-20-11-9-19(10-12-20)26-25(30)18-6-4-5-17(13-18)14-24(28)29/h2-13,21H,14-16H2,1H3,(H,26,30)(H,28,29)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem 19: 5361-71 (2011) Article DOI: 10.1016/j.bmc.2011.08.007 BindingDB Entry DOI: 10.7270/Q2X067DJ
					More data for this Ligand-Target Pair