new BindingDB logo
myBDB logout

BDBM50351662 CHEMBL1822366

SMILES: Brc1cc(cc2NC(=O)C(=NNC(=O)Cc3ccc4OCCc4c3)c12)C(=O)NCN1CCOCC1

InChI Key: InChIKey=RECDFYTYLHADHA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50351662
PNG
(CHEMBL1822366)
Show SMILES Brc1cc(cc2NC(=O)C(=NNC(=O)Cc3ccc4OCCc4c3)c12)C(=O)NCN1CCOCC1 |w:10.10|
Show InChI InChI=1S/C24H24BrN5O5/c25-17-11-16(23(32)26-13-30-4-7-34-8-5-30)12-18-21(17)22(24(33)27-18)29-28-20(31)10-14-1-2-19-15(9-14)3-6-35-19/h1-2,9,11-12H,3-8,10,13H2,(H,26,32)(H,28,31)(H,27,29,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 0.700n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair