BDBM50351778 CHEMBL1823760

SMILES: OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(F)c1

InChI Key: InChIKey=MJDYIONLNFPARI-UKTHLTGXSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1C (Homo sapiens (Human))	BDBM50351778 (CHEMBL1823760) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(F)c1 Show InChI InChI=1S/C29H23F2NO4/c30-24-6-3-4-19(15-24)9-13-28(33)32-27(29(34)35)16-20-8-10-22-17-25(12-11-21(22)14-20)36-18-23-5-1-2-7-26(23)31/h1-15,17,27H,16,18H2,(H,32,33)(H,34,35)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65E+4	n/a	n/a	n/a	n/a	8.0	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of human recombinant SHP1 in Tris buffer at pH 8 using OMPF as substrate				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50351778 (CHEMBL1823760) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(F)c1 Show InChI InChI=1S/C29H23F2NO4/c30-24-6-3-4-19(15-24)9-13-28(33)32-27(29(34)35)16-20-8-10-22-17-25(12-11-21(22)14-20)36-18-23-5-1-2-7-26(23)31/h1-15,17,27H,16,18H2,(H,32,33)(H,34,35)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of human recombinant CDC25B				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50351778 (CHEMBL1823760) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(F)c1 Show InChI InChI=1S/C29H23F2NO4/c30-24-6-3-4-19(15-24)9-13-28(33)32-27(29(34)35)16-20-8-10-22-17-25(12-11-21(22)14-20)36-18-23-5-1-2-7-26(23)31/h1-15,17,27H,16,18H2,(H,32,33)(H,34,35)/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of TCPTP				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50351778 (CHEMBL1823760) Show SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(F)c1 Show InChI InChI=1S/C29H23F2NO4/c30-24-6-3-4-19(15-24)9-13-28(33)32-27(29(34)35)16-20-8-10-22-17-25(12-11-21(22)14-20)36-18-23-5-1-2-7-26(23)31/h1-15,17,27H,16,18H2,(H,32,33)(H,34,35)/b13-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University Curated by ChEMBL					Assay Description Inhibition of PTP1B using p-nitrophenyl phosphate as substrate				Eur J Med Chem 46: 3630-8 (2011) Article DOI: 10.1016/j.ejmech.2011.05.027 BindingDB Entry DOI: 10.7270/Q2W09685
					More data for this Ligand-Target Pair