BindingDB PrimarySearch

BDBM50352152 CHEMBL1824785

SMILES: Fc1cccc(CN2C3CC4CC(C3)CC2C4)c1

InChI Key: InChIKey=HTDIUQCBNGOYTP-UHFFFAOYSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50352152
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 90 mins by scintillation counting				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of M4 muscarinic receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of M2 muscarinic receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of M5 muscarinic receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of NET transporter by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of alpha-1A adrenergic receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of H1 receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50352152 (CHEMBL1824785) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Inhibition of D1 dopamine receptor by NIMH PDSP				Bioorg Med Chem Lett 21: 5289-92 (2011) Article DOI: 10.1016/j.bmcl.2011.07.028 BindingDB Entry DOI: 10.7270/Q2S46SCV
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair