Found 6 hits for monomerid = 50352492 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human PKCalpha activity using Ser/Thr 7 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 5 (CDK5)
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human CDK5/p35 activity using Ser/Thr 12 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human GSK3alpha activity using Ser/Thr 11 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human CKI epsilon activity using Ser/Thr 11 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human AURKA activity using Ser/Thr 1 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50352492
(CHEMBL1824540)Show SMILES COc1ccc(CNC(=O)Nc2nc3ccc(cc3s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H14N4O4S/c1-24-12-5-2-10(3-6-12)9-17-15(21)19-16-18-13-7-4-11(20(22)23)8-14(13)25-16/h2-8H,9H2,1H3,(H2,17,18,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.64E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt
Curated by ChEMBL
| Assay Description Inhibition of human GSK3-beta activity using Ser/Thr 9 peptide as substrate by FRET assay |
Bioorg Med Chem Lett 21: 5610-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3 |
More data for this Ligand-Target Pair | |