BDBM50352525 CHEMBL1824869

SMILES: Nc1ncc(cc1OCc1ccccc1Cl)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1

InChI Key: InChIKey=GMHOIIVIWBAYBP-XMMPIXPASA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50352525 (CHEMBL1824869) Show SMILES Nc1ncc(cc1OCc1ccccc1Cl)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1 |r| Show InChI InChI=1S/C28H31ClN4O2/c29-25-8-2-1-6-22(25)19-35-26-16-23(17-31-27(26)30)20-9-11-21(12-10-20)28(34)33-15-5-7-24(33)18-32-13-3-4-14-32/h1-2,6,8-12,16-17,24H,3-5,7,13-15,18-19H2,(H2,30,31)/t24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assay				J Med Chem 54: 6342-63 (2011) Article DOI: 10.1021/jm2007613 BindingDB Entry DOI: 10.7270/Q2Q52Q09
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50352525 (CHEMBL1824869) Show SMILES Nc1ncc(cc1OCc1ccccc1Cl)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1 |r| Show InChI InChI=1S/C28H31ClN4O2/c29-25-8-2-1-6-22(25)19-35-26-16-23(17-31-27(26)30)20-9-11-21(12-10-20)28(34)33-15-5-7-24(33)18-32-13-3-4-14-32/h1-2,6,8-12,16-17,24H,3-5,7,13-15,18-19H2,(H2,30,31)/t24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA method				J Med Chem 54: 6342-63 (2011) Article DOI: 10.1021/jm2007613 BindingDB Entry DOI: 10.7270/Q2Q52Q09
					More data for this Ligand-Target Pair