BDBM50352526 CHEMBL1824870

SMILES: Nc1ncc(cc1OCc1ccccc1C#N)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1

InChI Key: InChIKey=NHXSULDTYDKXNA-AREMUKBSSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50352526 (CHEMBL1824870) Show SMILES Nc1ncc(cc1OCc1ccccc1C#N)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1 |r| Show InChI InChI=1S/C29H31N5O2/c30-17-23-6-1-2-7-24(23)20-36-27-16-25(18-32-28(27)31)21-9-11-22(12-10-21)29(35)34-15-5-8-26(34)19-33-13-3-4-14-33/h1-2,6-7,9-12,16,18,26H,3-5,8,13-15,19-20H2,(H2,31,32)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assay				J Med Chem 54: 6342-63 (2011) Article DOI: 10.1021/jm2007613 BindingDB Entry DOI: 10.7270/Q2Q52Q09
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50352526 (CHEMBL1824870) Show SMILES Nc1ncc(cc1OCc1ccccc1C#N)-c1ccc(cc1)C(=O)N1CCC[C@@H]1CN1CCCC1 |r| Show InChI InChI=1S/C29H31N5O2/c30-17-23-6-1-2-7-24(23)20-36-27-16-25(18-32-28(27)31)21-9-11-22(12-10-21)29(35)34-15-5-8-26(34)19-33-13-3-4-14-33/h1-2,6-7,9-12,16,18,26H,3-5,8,13-15,19-20H2,(H2,31,32)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA method				J Med Chem 54: 6342-63 (2011) Article DOI: 10.1021/jm2007613 BindingDB Entry DOI: 10.7270/Q2Q52Q09
					More data for this Ligand-Target Pair