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BDBM50352633 CHEMBL1822311

SMILES: NCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12

InChI Key: InChIKey=LOIBJZYMXKAYQI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352633   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
c-Jun N-terminal kinase, JNK


(Homo sapiens (Human))
BDBM50352633
PNG
(CHEMBL1822311)
Show SMILES NCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12
Show InChI InChI=1S/C17H18N4O/c18-10-3-11-19-17(22)13-8-6-12(7-9-13)16-14-4-1-2-5-15(14)20-21-16/h1-2,4-9H,3,10-11,18H2,(H,19,22)(H,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK1 using ATF2 substrate by TR-FRET assay


J Med Chem 54: 6206-14 (2011)


Article DOI: 10.1021/jm200479c
BindingDB Entry DOI: 10.7270/Q2668DMM
More data for this
Ligand-Target Pair