BDBM50352633 CHEMBL1822311

SMILES: NCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12

InChI Key: InChIKey=LOIBJZYMXKAYQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50352633 (CHEMBL1822311) Show SMILES NCCCNC(=O)c1ccc(cc1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C17H18N4O/c18-10-3-11-19-17(22)13-8-6-12(7-9-13)16-14-4-1-2-5-15(14)20-21-16/h1-2,4-9H,3,10-11,18H2,(H,19,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 using ATF2 substrate by TR-FRET assay				J Med Chem 54: 6206-14 (2011) Article DOI: 10.1021/jm200479c BindingDB Entry DOI: 10.7270/Q2668DMM
					More data for this Ligand-Target Pair