BDBM50352901 CHEMBL1824897

SMILES: C[C@H]1CN(CCN1)C(=O)c1c(Oc2cc(F)ccc2C)n(C2CCCCC2)c2cc(=O)[nH]cc12

InChI Key: InChIKey=AKLMVXPTDFTPSA-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50352901 (CHEMBL1824897) Show SMILES C[C@H]1CN(CCN1)C(=O)c1c(Oc2cc(F)ccc2C)n(C2CCCCC2)c2cc(=O)[nH]cc12 |r| Show InChI InChI=1S/C26H31FN4O3/c1-16-8-9-18(27)12-22(16)34-26-24(25(33)30-11-10-28-17(2)15-30)20-14-29-23(32)13-21(20)31(26)19-6-4-3-5-7-19/h8-9,12-14,17,19,28H,3-7,10-11,15H2,1-2H3,(H,29,32)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant human renin using Dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate after 2 hrs by spectrofluorom...				Bioorg Med Chem Lett 21: 5487-92 (2011) Article DOI: 10.1016/j.bmcl.2011.06.112 BindingDB Entry DOI: 10.7270/Q2RX9CFJ
					More data for this Ligand-Target Pair