BDBM50353034 CHEMBL1302748

SMILES: COc1cc(ccc1O)C1Nc2cccc3cccc(N1)c23

InChI Key: InChIKey=YRGCJUJHYQYQHQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50353034 (CHEMBL1302748) Show SMILES COc1cc(ccc1O)C1Nc2cccc3cccc(N1)c23 Show InChI InChI=1S/C18H16N2O2/c1-22-16-10-12(8-9-15(16)21)18-19-13-6-2-4-11-5-3-7-14(20-18)17(11)13/h2-10,18-21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of human AR AF2 site expressed in human LNCap cells coexpressing eGFP -ARR2PB assessed as inhibition of transcriptional activity				J Med Chem 54: 6197-205 (2011) Article DOI: 10.1021/jm200532b BindingDB Entry DOI: 10.7270/Q20G3KHB
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50353034 (CHEMBL1302748) Show SMILES COc1cc(ccc1O)C1Nc2cccc3cccc(N1)c23 Show InChI InChI=1S/C18H16N2O2/c1-22-16-10-12(8-9-15(16)21)18-19-13-6-2-4-11-5-3-7-14(20-18)17(11)13/h2-10,18-21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Displacement of SRC2-3 peptide from human AR ligand binding site expressed in Escherichia coli BL21 by AF2 FP assay				J Med Chem 54: 6197-205 (2011) Article DOI: 10.1021/jm200532b BindingDB Entry DOI: 10.7270/Q20G3KHB
					More data for this Ligand-Target Pair