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BDBM50353182 CHEMBL1829501

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1cn(-[#6]-[#6@H](-[#7]-[#6](=O)-c2ccccc2-[#8]-c2ccccc2)-[#6](-[#8])=O)nn1

InChI Key: InChIKey=PFFJPRTXSCCLIU-DBZIORCRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353182   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Homo sapiens (Human))		BDBM50353182
PNG
(CHEMBL1829501)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1cn(-[#6]-[#6@H](-[#7]-[#6](=O)-c2ccccc2-[#8]-c2ccccc2)-[#6](-[#8])=O)nn1 |r|
Show InChI InChI=1S/C33H40N4O4/c1-24(2)12-10-13-25(3)14-11-15-26(4)20-21-27-22-37(36-35-27)23-30(33(39)40)34-32(38)29-18-8-9-19-31(29)41-28-16-6-5-7-17-28/h5-9,12,14,16-20,22,30H,10-11,13,15,21,23H2,1-4H3,(H,34,38)(H,39,40)/b25-14+,26-20+/t30-/m0/s1
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.94E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human ICMT by vapor diffusion assay

Bioorg Med Chem Lett 21: 5616-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.053
BindingDB Entry DOI: 10.7270/Q2Q240MD
More data for this
Ligand-Target Pair