BDBM50353743 CHEMBL1830985

SMILES: CN(Cc1ccccc1)Cc1ccccc1CNc1ccnc2cc(Cl)ccc12

InChI Key: InChIKey=KCCAYCIGOLFFDQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chloroquine resistance transporter (Plasmodium falciparum)	BDBM50353743 (CHEMBL1830985) Show SMILES CN(Cc1ccccc1)Cc1ccccc1CNc1ccnc2cc(Cl)ccc12 Show InChI InChI=1S/C25H24ClN3/c1-29(17-19-7-3-2-4-8-19)18-21-10-6-5-9-20(21)16-28-24-13-14-27-25-15-22(26)11-12-23(24)25/h2-15H,16-18H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi...				J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN
					More data for this Ligand-Target Pair