BDBM50353745 CHEMBL1830987
SMILES: CN(Cc1ccccc1)Cc1ccc(CNc2ccnc3cc(Cl)ccc23)cc1
InChI Key: InChIKey=KRFAQKYUWVQMIX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50353745 (CHEMBL1830987) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cape Town Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi... | J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN | |||||||||||
More data for this Ligand-Target Pair |