BindingDB PrimarySearch

BDBM50353901 CHEMBL1829958

SMILES: Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12

InChI Key: InChIKey=CXLPBBKWDIYIPK-UHFFFAOYSA-N

Data: 2 KI 7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50353901
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]5-carboximidotryptamine from 5-HT1D receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]SCH233930 from dopamine D5 receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]QNB from muscarinic acetylcholine M5 receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5-HT7 receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from DAT after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5-HT2B receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50353901 (CHEMBL1829958) Show SMILES Nc1nc(Br)ncc1-c1c[nH]c2cccc(O)c12 Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation counting				Bioorg Med Chem 19: 5756-62 (2011) Article DOI: 10.1016/j.bmc.2011.08.033 BindingDB Entry DOI: 10.7270/Q25X29BF
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair