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BDBM50354206 CHEMBL1836000

SMILES: CN([C@@H]1CCN(C1)C1CCCC1)C(=O)c1ccc(cc1)-n1cccn1

InChI Key: InChIKey=MKCPKLRBORNGKZ-LJQANCHMSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354206   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50354206
PNG
(CHEMBL1836000)
Show SMILES CN([C@@H]1CCN(C1)C1CCCC1)C(=O)c1ccc(cc1)-n1cccn1 |r|
Show InChI InChI=1S/C20H26N4O/c1-22(19-11-14-23(15-19)17-5-2-3-6-17)20(25)16-7-9-18(10-8-16)24-13-4-12-21-24/h4,7-10,12-13,17,19H,2-3,5-6,11,14-15H2,1H3/t19-/m1/s1
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Similars
Article
PubMed
 3.60n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]-(R)alpha-methylhistamine from human histamine H3 receptor expressed in human HEK293T cells

Bioorg Med Chem Lett 21: 5957-60 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.061
BindingDB Entry DOI: 10.7270/Q2QN6753
More data for this
Ligand-Target Pair