BDBM50354211 CHEMBL1836037
SMILES: CN([C@@H]1CCN(C1)C1CCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12
InChI Key: InChIKey=DNXMXCCCVCPJES-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50354211 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50354211
(CHEMBL1836037)Show SMILES CN([C@@H]1CCN(C1)C1CCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12 |r| Show InChI InChI=1S/C24H28N4O/c1-17-25-22-8-3-4-9-23(22)28(17)20-12-10-18(11-13-20)24(29)26(2)21-14-15-27(16-21)19-6-5-7-19/h3-4,8-13,19,21H,5-7,14-16H2,1-2H3/t21-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(R)alpha-methylhistamine from human histamine H3 receptor expressed in human HEK293T cells |
Bioorg Med Chem Lett 21: 5957-60 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.061
BindingDB Entry DOI: 10.7270/Q2QN6753 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50354211
(CHEMBL1836037)Show SMILES CN([C@@H]1CCN(C1)C1CCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12 |r| Show InChI InChI=1S/C24H28N4O/c1-17-25-22-8-3-4-9-23(22)28(17)20-12-10-18(11-13-20)24(29)26(2)21-14-15-27(16-21)19-6-5-7-19/h3-4,8-13,19,21H,5-7,14-16H2,1-2H3/t21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 5957-60 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.061
BindingDB Entry DOI: 10.7270/Q2QN6753 |
More data for this
Ligand-Target Pair | |
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