BDBM50354212 CHEMBL1836039
SMILES: CN([C@@H]1CCN(C1)C1CCCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12
InChI Key: InChIKey=VTYNAGSOHIRPRR-JOCHJYFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50354212 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50354212
(CHEMBL1836039)Show SMILES CN([C@@H]1CCN(C1)C1CCCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12 |r| Show InChI InChI=1S/C25H30N4O/c1-18-26-23-9-5-6-10-24(23)29(18)21-13-11-19(12-14-21)25(30)27(2)22-15-16-28(17-22)20-7-3-4-8-20/h5-6,9-14,20,22H,3-4,7-8,15-17H2,1-2H3/t22-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]-(R)alpha-methylhistamine from human histamine H3 receptor expressed in human HEK293T cells |
Bioorg Med Chem Lett 21: 5957-60 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.061
BindingDB Entry DOI: 10.7270/Q2QN6753 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50354212
(CHEMBL1836039)Show SMILES CN([C@@H]1CCN(C1)C1CCCC1)C(=O)c1ccc(cc1)-n1c(C)nc2ccccc12 |r| Show InChI InChI=1S/C25H30N4O/c1-18-26-23-9-5-6-10-24(23)29(18)21-13-11-19(12-14-21)25(30)27(2)22-15-16-28(17-22)20-7-3-4-8-20/h5-6,9-14,20,22H,3-4,7-8,15-17H2,1-2H3/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 21: 5957-60 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.061
BindingDB Entry DOI: 10.7270/Q2QN6753 |
More data for this
Ligand-Target Pair | |
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