Found 4 hits for monomerid = 50354334 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50354334
(CHEMBL1836629)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C15H19IN4O7S2/c16-14-9(6-28-15-13(24)12(23)11(22)10(5-21)27-15)18-19-20(14)7-1-3-8(4-2-7)29(17,25)26/h1-4,10-13,15,21-24H,5-6H2,(H2,17,25,26)/t10-,11-,12+,13-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA2 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50354334
(CHEMBL1836629)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C15H19IN4O7S2/c16-14-9(6-28-15-13(24)12(23)11(22)10(5-21)27-15)18-19-20(14)7-1-3-8(4-2-7)29(17,25)26/h1-4,10-13,15,21-24H,5-6H2,(H2,17,25,26)/t10-,11-,12+,13-,15+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA9 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50354334
(CHEMBL1836629)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C15H19IN4O7S2/c16-14-9(6-28-15-13(24)12(23)11(22)10(5-21)27-15)18-19-20(14)7-1-3-8(4-2-7)29(17,25)26/h1-4,10-13,15,21-24H,5-6H2,(H2,17,25,26)/t10-,11-,12+,13-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 10.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA12 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50354334
(CHEMBL1836629)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C15H19IN4O7S2/c16-14-9(6-28-15-13(24)12(23)11(22)10(5-21)27-15)18-19-20(14)7-1-3-8(4-2-7)29(17,25)26/h1-4,10-13,15,21-24H,5-6H2,(H2,17,25,26)/t10-,11-,12+,13-,15+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 119 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA1 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |