Found 4 hits for monomerid = 50354338 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50354338
(CHEMBL1836632)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C21H29IN4O14S2/c22-19-10(24-25-26(19)8-1-3-9(4-2-8)42(23,36)37)7-41(34,35)21-17(33)15(31)18(12(6-28)39-21)40-20-16(32)14(30)13(29)11(5-27)38-20/h1-4,11-18,20-21,27-33H,5-7H2,(H2,23,36,37)/t11-,12-,13-,14+,15-,16-,17-,18-,20-,21+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 11.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA12 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50354338
(CHEMBL1836632)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C21H29IN4O14S2/c22-19-10(24-25-26(19)8-1-3-9(4-2-8)42(23,36)37)7-41(34,35)21-17(33)15(31)18(12(6-28)39-21)40-20-16(32)14(30)13(29)11(5-27)38-20/h1-4,11-18,20-21,27-33H,5-7H2,(H2,23,36,37)/t11-,12-,13-,14+,15-,16-,17-,18-,20-,21+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 59.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA2 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50354338
(CHEMBL1836632)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C21H29IN4O14S2/c22-19-10(24-25-26(19)8-1-3-9(4-2-8)42(23,36)37)7-41(34,35)21-17(33)15(31)18(12(6-28)39-21)40-20-16(32)14(30)13(29)11(5-27)38-20/h1-4,11-18,20-21,27-33H,5-7H2,(H2,23,36,37)/t11-,12-,13-,14+,15-,16-,17-,18-,20-,21+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA9 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50354338
(CHEMBL1836632)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nnc(CS(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)c1I |r| Show InChI InChI=1S/C21H29IN4O14S2/c22-19-10(24-25-26(19)8-1-3-9(4-2-8)42(23,36)37)7-41(34,35)21-17(33)15(31)18(12(6-28)39-21)40-20-16(32)14(30)13(29)11(5-27)38-20/h1-4,11-18,20-21,27-33H,5-7H2,(H2,23,36,37)/t11-,12-,13-,14+,15-,16-,17-,18-,20-,21+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA1 by CO2 hydration based stopped flow assay |
J Med Chem 54: 6905-18 (2011)
Article DOI: 10.1021/jm200892s BindingDB Entry DOI: 10.7270/Q2BG2PDZ |
More data for this Ligand-Target Pair | |