Found 4 hits for monomerid = 50354426 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 6
(Homo sapiens (Human)) | BDBM50354426
(CHEMBL1836864)Show SMILES Cc1cn2c(cnc2c(Nc2ccc(cc2F)C(=O)N2CCNC(C)(C)C2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C23H25FN8O/c1-14-12-32-19(16-9-27-28-10-16)11-25-21(32)20(29-14)30-18-5-4-15(8-17(18)24)22(33)31-7-6-26-23(2,3)13-31/h4-5,8-12,26H,6-7,13H2,1-3H3,(H,27,28)(H,29,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of BRK pretreated for 30 mins by microplate reader |
Bioorg Med Chem Lett 21: 5870-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.101
BindingDB Entry DOI: 10.7270/Q2PR7WCR |
More data for this
Ligand-Target Pair | |
Protein-tyrosine kinase 6
(Homo sapiens (Human)) | BDBM50354426
(CHEMBL1836864)Show SMILES Cc1cn2c(cnc2c(Nc2ccc(cc2F)C(=O)N2CCNC(C)(C)C2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C23H25FN8O/c1-14-12-32-19(16-9-27-28-10-16)11-25-21(32)20(29-14)30-18-5-4-15(8-17(18)24)22(33)31-7-6-26-23(2,3)13-31/h4-5,8-12,26H,6-7,13H2,1-3H3,(H,27,28)(H,29,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrs |
Bioorg Med Chem Lett 21: 5870-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.101
BindingDB Entry DOI: 10.7270/Q2PR7WCR |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50354426
(CHEMBL1836864)Show SMILES Cc1cn2c(cnc2c(Nc2ccc(cc2F)C(=O)N2CCNC(C)(C)C2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C23H25FN8O/c1-14-12-32-19(16-9-27-28-10-16)11-25-21(32)20(29-14)30-18-5-4-15(8-17(18)24)22(33)31-7-6-26-23(2,3)13-31/h4-5,8-12,26H,6-7,13H2,1-3H3,(H,27,28)(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of LCK |
Bioorg Med Chem Lett 21: 5870-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.101
BindingDB Entry DOI: 10.7270/Q2PR7WCR |
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50354426
(CHEMBL1836864)Show SMILES Cc1cn2c(cnc2c(Nc2ccc(cc2F)C(=O)N2CCNC(C)(C)C2)n1)-c1cn[nH]c1 Show InChI InChI=1S/C23H25FN8O/c1-14-12-32-19(16-9-27-28-10-16)11-25-21(32)20(29-14)30-18-5-4-15(8-17(18)24)22(33)31-7-6-26-23(2,3)13-31/h4-5,8-12,26H,6-7,13H2,1-3H3,(H,27,28)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of AurB |
Bioorg Med Chem Lett 21: 5870-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.101
BindingDB Entry DOI: 10.7270/Q2PR7WCR |
More data for this
Ligand-Target Pair | |
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