BDBM50355577 CHEMBL1910605

SMILES: Cc1cn2c(\C=N/NC(N)=N)c(nc2s1)-c1ccc(F)cc1

InChI Key: InChIKey=BMIJOLMGBAUKDY-FXBPXSCXSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50355577 (CHEMBL1910605) Show SMILES Cc1cn2c(\C=N/NC(N)=N)c(nc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H13FN6S/c1-8-7-21-11(6-18-20-13(16)17)12(19-14(21)22-8)9-2-4-10(15)5-3-9/h2-7H,1H3,(H4,16,17,20)/b18-6-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50355577 (CHEMBL1910605) Show SMILES Cc1cn2c(\C=N/NC(N)=N)c(nc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H13FN6S/c1-8-7-21-11(6-18-20-13(16)17)12(19-14(21)22-8)9-2-4-10(15)5-3-9/h2-7H,1H3,(H4,16,17,20)/b18-6-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355577 (CHEMBL1910605) Show SMILES Cc1cn2c(\C=N/NC(N)=N)c(nc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H13FN6S/c1-8-7-21-11(6-18-20-13(16)17)12(19-14(21)22-8)9-2-4-10(15)5-3-9/h2-7H,1H3,(H4,16,17,20)/b18-6-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair