BDBM50355586 CHEMBL1910376

SMILES: Cc1nn2c(\C=N\NC(N)=N)c(nc2s1)-c1cc(Cl)sc1Cl

InChI Key: InChIKey=CHJVYGVSYSSJQB-HQYXKAPLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50355586 (CHEMBL1910376) Show SMILES Cc1nn2c(\C=N\NC(N)=N)c(nc2s1)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C11H9Cl2N7S2/c1-4-19-20-6(3-16-18-10(14)15)8(17-11(20)21-4)5-2-7(12)22-9(5)13/h2-3H,1H3,(H4,14,15,18)/b16-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355586 (CHEMBL1910376) Show SMILES Cc1nn2c(\C=N\NC(N)=N)c(nc2s1)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C11H9Cl2N7S2/c1-4-19-20-6(3-16-18-10(14)15)8(17-11(20)21-4)5-2-7(12)22-9(5)13/h2-3H,1H3,(H4,14,15,18)/b16-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair