BDBM50355596 CHEMBL1910624

SMILES: Clc1cc(c(Cl)s1)-c1nc2ccccn2c1-[#6]=[#7]\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#7]-1

InChI Key: InChIKey=ZEDGGXNENVOOSF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50355596 (CHEMBL1910624) Show SMILES Clc1cc(c(Cl)s1)-c1nc2ccccn2c1-[#6]=[#7]\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#7]-1 |w:16.18| Show InChI InChI=1S/C15H12Cl2N6S/c16-11-7-9(14(17)24-11)13-10(8-20-22-15-18-4-5-19-15)23-6-2-1-3-12(23)21-13/h1-3,6-8H,4-5H2,(H2,18,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355596 (CHEMBL1910624) Show SMILES Clc1cc(c(Cl)s1)-c1nc2ccccn2c1-[#6]=[#7]\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#7]-1 |w:16.18| Show InChI InChI=1S/C15H12Cl2N6S/c16-11-7-9(14(17)24-11)13-10(8-20-22-15-18-4-5-19-15)23-6-2-1-3-12(23)21-13/h1-3,6-8H,4-5H2,(H2,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair