null

SMILES: NC(=N)N\N=C\c1c(nc2sccn12)-c1cc(Cl)sc1Cl

InChI Key: InChIKey=KYILJEHHCLLGAI-AYSLTRBKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50355603 (CHEMBL1910757) Show SMILES NC(=N)N\N=C\c1c(nc2sccn12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C11H8Cl2N6S2/c12-7-3-5(9(13)21-7)8-6(4-16-18-10(14)15)19-1-2-20-11(19)17-8/h1-4H,(H4,14,15,18)/b16-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50355603 (CHEMBL1910757) Show SMILES NC(=N)N\N=C\c1c(nc2sccn12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C11H8Cl2N6S2/c12-7-3-5(9(13)21-7)8-6(4-16-18-10(14)15)19-1-2-20-11(19)17-8/h1-4H,(H4,14,15,18)/b16-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355603 (CHEMBL1910757) Show SMILES NC(=N)N\N=C\c1c(nc2sccn12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C11H8Cl2N6S2/c12-7-3-5(9(13)21-7)8-6(4-16-18-10(14)15)19-1-2-20-11(19)17-8/h1-4H,(H4,14,15,18)/b16-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair