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BDBM50355609 CHEMBL1909651

SMILES: NC(=N)N\N=C/c1c(nc2sccn12)-c1ccc(Br)c(c1)[N+]([O-])=O

InChI Key: InChIKey=UTYZCXQWQGJXFB-FMQZQXMHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM50355609
PNG
(CHEMBL1909651)
Show SMILES NC(=N)N\N=C/c1c(nc2sccn12)-c1ccc(Br)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H10BrN7O2S/c14-8-2-1-7(5-9(8)21(22)23)11-10(6-17-19-12(15)16)20-3-4-24-13(20)18-11/h1-6H,(H4,15,16,19)/b17-6-
PDB
MMDB

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KEGG

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ di Bologna

Curated by ChEMBL


Assay Description
Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay


Eur J Med Chem 46: 4311-23 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.001
BindingDB Entry DOI: 10.7270/Q2NG4R1D
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM50355609
PNG
(CHEMBL1909651)
Show SMILES NC(=N)N\N=C/c1c(nc2sccn12)-c1ccc(Br)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H10BrN7O2S/c14-8-2-1-7(5-9(8)21(22)23)11-10(6-17-19-12(15)16)20-3-4-24-13(20)18-11/h1-6H,(H4,15,16,19)/b17-6-
PDB
MMDB

Reactome pathway
KEGG

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UniProtKB/TrEMBL

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DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.67E+4n/an/an/an/an/an/a



Universit£ di Bologna

Curated by ChEMBL


Assay Description
Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay


Eur J Med Chem 46: 4311-23 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.001
BindingDB Entry DOI: 10.7270/Q2NG4R1D
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50355609
PNG
(CHEMBL1909651)
Show SMILES NC(=N)N\N=C/c1c(nc2sccn12)-c1ccc(Br)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H10BrN7O2S/c14-8-2-1-7(5-9(8)21(22)23)11-10(6-17-19-12(15)16)20-3-4-24-13(20)18-11/h1-6H,(H4,15,16,19)/b17-6-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ di Bologna

Curated by ChEMBL


Assay Description
Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay


Eur J Med Chem 46: 4311-23 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.001
BindingDB Entry DOI: 10.7270/Q2NG4R1D
More data for this
Ligand-Target Pair